He prescribed garlic to treat a variety of medical conditions — and modern science has confirmed many of these beneficial health effects.Garlic grows in many parts of the world and is a popular ingredient in cooking, due to its strong smell and delicious taste.Its use was well documented by many major civilizations, including the Egyptians, Babylonians, Greeks, Romans, and Chinese ( 1 ).Other compounds that may play a role in garlic’s health benefits include diallyl disulfide and s-allyl cysteine ( 3 ).Summary Garlic is a plant in the onion family that’s grown for its distinctive taste and health benefits.A large, 12-week study found that a daily garlic supplement reduced the number of colds by 63% compared with a placebo ( 5 ).Summary Garlic supplements may help prevent and reduce the severity of illnesses like the flu and common cold, but more research needs to be done before any conclusions can be made.The active compounds in garlic can reduce blood pressure Cardiovascular diseases like heart attack and stroke are responsible for more deaths than almost any other condition ( 8 ).In one study, 600–1,500 mg of aged garlic extract were just as effective as the drug Atenolol at reducing blood pressure over a 24-week period ( 12 ).Garlic contains antioxidants that may help prevent Alzheimer’s disease and dementia Oxidative damage from free radicals contributes to the aging process.But given the beneficial effects on important risk factors like blood pressure, it makes sense that garlic could help you live longer.The fact that it can fight infectious diseases is also an important factor, because these are common causes of death, especially in the elderly or people with dysfunctional immune systems ( 23 ).Summary Garlic has known beneficial effects on common causes of chronic disease, so it makes sense that it could also help you live longer.It was traditionally used in ancient cultures to reduce fatigue and improve the work capacity of laborers.Summary Garlic may improve physical performance in lab animals and people with heart disease.Summary Garlic was shown to significantly reduce lead toxicity and related symptoms in one study.However, rodent studies have shown that it can minimize bone loss by increasing estrogen in females ( 27 , 28 , 29 , 30 ).Summary Garlic appears to have some benefits for bone health by increasing estrogen levels in females, but more human studies are needed.Garlic is easy to include in your diet and adds flavor The last one is not a health benefit but is still important. .
6 Garlic Benefits To Boost Your Health – Cleveland Clinic
Dietitian Laura Jeffers, MEd, RD, LD, offers six surprising ways that this herb-like vegetable boosts your health.“Garlic gets its pungent smell from an organic sulfur compound called allicin,” Jeffers says.According to one study involving 41,000 women between the ages of 55 and 69, those who routinely ate garlic, fruits and vegetables had a 35% lower colon cancer risk.Researchers believe red blood cells turn the sulfur in garlic into hydrogen sulfide gas.Before putting your blood pressure medication away, though, consult your doctor to see if adding more garlic to your diet could be beneficial for you.Those same antibacterial properties in fresh garlic can kill the bacteria that lead to food poisoning, including salmonella and E.coli.The enzymes from the allicin need a few minutes to start working, so let it sit after you mince, crush or chop it.Higher temperatures kill the allicin, so add garlic to your recipes when you’re almost done cooking.”.On rare occasions, garlic supplements can cause headaches, fatigue, appetite loss, muscle aches, dizziness and allergic reactions like asthma attacks or skin rashes.“You may also get a stinging feeling on the skin if you handle significant amounts of fresh and dried garlic,” says Jeffers.Overdoing it can cause discomfort, including upset stomach, bloating, diarrhea, body odor and bad breath. .
GARLIC: Overview, Uses, Side Effects, Precautions, Interactions
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Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats.Omurtag, G. Z., Guranlioglu, F.
D., Sehirli, O., Arbak, S., Uslu, B., Gedik, N., and Sener, G. Protective effect of aqueous garlic extract against naphthalene-induced oxidative stress in mice.Orekhov A and Tertov V.
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Allium vegetables: their role in the prevention of cancer.Aged garlic extract improves endothelial function in men with coronary artery disease.Wongmekiat, O. and Thamprasert, K.
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J., Shu, X. O., Gao, Y.
T., Ji, B. T., Ziegler, R. G., and Fraumeni, J. F., Jr.Reduction in elevated blood lipids in hospitalised patients by a standardised garlic preparation.Ackermann RT, Mulrow CD, Ramirez G, et al. Garlic shows promise for improving some cardiovascular risk factors.Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men.Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men.Effect of topical garlic on wound healing and scarring: A clinical trial.Ali M, Bordia T, Mustafa T. Effect of raw versus boiled aqueous extract of garlic and onion on platelet aggregation.Ali M, Thomson M, Afzal M.
Garlic and onions: their effect on eicosanoid metabolism and its clinical relevance.The Effect of Garlic Tablets on the Endometriosis-Related Pains: A Randomized Placebo-Controlled Clinical Trial.Hussain, S. P., Jannu, L. N., and Rao, A. R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice.Huynh F, Fowkes C, and Tejani A. Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients.Aged garlic extract and its constituents inhibit Cu2+ -induced oxidative modification of low density lipoprotein.Ishikawa, H., Saeki, T., Otani, T., Suzuki, T., Shimozuma, K., Nishino, H., Fukuda, S., and Morimoto, K.
Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.Jabbari, A., Argani, H., Ghorbanihaghjo, A., and Mahdavi, R. Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in Renal Transplant Recipients.Jain, R.
C. Effect of garlic on serum lipids, coagulability and fibrinolytic activity of blood.Gupta, N. and Porter, T. D. Garlic and garlic-derived compounds inhibit human squalene monooxygenase.Hajheydari, Z., Jamshidi, M., Akbari, J., and Mohammadpour, R. Combination of topical garlic gel and betamethasone valerate cream in the treatment of localized alopecia areata: a double-blind randomized controlled study.Hansson LE, Nyren O, and Bergstrom R.
Diet and risk of gastric cancer: a population-based case-control study in Sweden.Harenberg, J., Giese, C., and Zimmermann, R. Effect of dried garlic on blood coagulation, fibrinolysis, platelet aggregation and serum cholesterol levels in patients with hyperlipoproteinemia.Hasani-Ranjbar, S., Larijani, B., and Abdollahi, M.
A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases.Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review.Hassan, Z. M., Yaraee, R., Zare, N., Ghazanfari, T., Sarraf Nejad, A. H., and Nazori, B. Immunomodulatory affect of R10 fraction of garlic extract on natural killer activity.Helen, A., Krishnakumar, K., Vijayammal, P. L., and Augusti, K.
T. A comparative study of antioxidants S-allyl cysteine sulfoxide and vitamin E on the damages induced by nicotine in rats.Henning, S.
M., Zhang, Y., Seeram, N. P., Lee, R.
P., Wang, P., Bowerman, S., and Heber, D. Antioxidant capacity and phytochemical content of herbs and spices in dry, fresh and blended herb paste form.Higashikawa, F., Noda, M., Awaya, T., Ushijima, M., and Sugiyama, M. Reduction of serum lipids by the intake of the extract of garlic fermented with Monascus pilosus: a randomized, double-blind, placebo-controlled clinical trial.Hikino, H., Tohkin, M., Kiso, Y., Namiki, T., Nishimura, S., and Takeyama, K.
Antihepatotoxic actions of Allium sativum bulbs.Hiltunen, R., Josling, P. D., and James, M.
H. Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel).Hirsch, K., Danilenko, M., Giat, J., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Levy, J., and Sharoni, Y.Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation.Hsu, C.
C., Huang, C. N., Hung, Y.
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Five cysteine-containing compounds have antioxidative activity in Balb/cA mice.Hu, J., Nyren, O., Wolk, A., Bergstrom, R., Yuen, J., Adami, H. O., Guo, L., Li, H., Huang, G., Xu, X., and .Hughes BG, Murray BK, North JA, and et al. Antiviral constituents from Allium sativum.Hughes, T. M., Varma, S., and Stone, N.
M. Occupational contact dermatitis from a garlic and herb mixture.Hurley, M.
N., Forrester, D. L., and Smyth, A.
R. Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis.Feldberg, R. S., Chang, S.
C., Kotik, A. N., Nadler, M., Neuwirth, Z., Sundstrom, D. C., and Thompson, N.
H. In vitro mechanism of inhibition of bacterial cell growth by allicin.Friedman, T., Shalom, A., and Westreich, M.
Self-inflicted garlic burns: our experience and literature review.Gaddoni G, Selvi M, Resta F, and et al. Allergic contact dermatitis to garlic in a cook.Gail M, You WC, Chang YS, and et al. Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: Design issues and initial data.Gail, M.
H. and You, W. C. A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions.Galduroz, J.
C., Antunes, H. K., and Santos, R.
F. Gender- and age-related variations in blood viscosity in normal volunteers: a study of the effects of extract of Allium sativum and Ginkgo biloba.Gallwitz, H., Bonse, S., Martinez-Cruz, A., Schlichting, I., Schumacher, K., and Krauth-Siegel, R. L. Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: crystallographic, kinetic, and spectroscopic studies.Gamboa-Leon, M. R., Aranda-Gonzalez, I., Mut-Martin, M., Garcia-Miss, M. R., and Dumonteil, E.
In vivo and in vitro control of Leishmania mexicana due to garlic-induced NO production.Gao YT, McLaughlin JK, and Gridley G. Risk factors for esophageal cancer in Shanghai, China.Gao, C.
M., Takezaki, T., Ding, J. H., Li, M.
S., and Tajima, K. Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China.Effect of garlic supplementation on plasma lipids in hypercholesterolemic men and women.Gebhardt R, Beck H, and Wagner K. Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells.Germain, E., Auger, J., Ginies, C., Siess, M. H., and Teyssier, C. In vivo metabolism of diallyl disulphide in the rat: identification of two new metabolites.Ghannoum, M. A.
Inhibition of Candida adhesion to buccal epithelial cells by an aqueous extract of Allium sativum (garlic).Studies on the anticandidal mode of action of Allium sativum (garlic).Ghazanfari, T., Hassan, Z. M., and Khamesipour, A.
Enhancement of peritoneal macrophage phagocytic activity against Leishmania major by garlic (Allium sativum) treatment.Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, and Willett WC.Intake of fat, meat, and fiber in relation to risk of colon cancer in men.Groppo, F. C., Ramacciato, J. C., Motta, R.
H., Ferraresi, P. M., and Sartoratto, A. Antimicrobial activity of garlic against oral streptococci.Groppo, F. C., Ramacciato, J.
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M., and Sartoratto, A. Antimicrobial activity of garlic, tea tree oil, and chlorhexidine against oral microorganisms.Guo, N. L., Lu, D. P., Woods, G. L., Reed, E., Zhou, G. Z., Zhang, L.
B., and Waldman, R. H. Demonstration of the anti-viral activity of garlic extract against human cytomegalovirus in vitro.Guo, Y., Zhang, K., Wang, Q., Li, Z., Yin, Y., Xu, Q., Duan, W., and Li, C. Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis.Dorant, E., van den Brandt, P.
A., Goldbohm, R. A., and Sturmans, F.
Consumption of onions and a reduced risk of stomach carcinoma.A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L.
Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial.Durak, I., Kavutcu, M., Aytac, B., Avci, A., Devrim, E., Ozbek, H., and Ozturk, H. S. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol.Dwivedi, C., John, L. M., Schmidt, D. S., and Engineer, F. N.
Effects of oil-soluble organosulfur compounds from garlic on doxorubicin-induced lipid peroxidation.Egen-Schwind C, Eckard R, Jekat FW, and et al. Pharmacokinetics of vinyldithiins, transformation products of allicin.Eguchi, A., Murakami, A., and Ohigashi, H. Novel bioassay system for evaluating anti-oxidative activities of food items: use of basolateral media from differentiated Caco-2 cells.El Beshbishy, H. A.
Aqueous garlic extract attenuates hepatitis and oxidative stress induced by galactosamine/lipoploysaccharide in rats.Eming, S. A., Piontek, J.
O., Hunzelmann, N., Rasokat, H., and Scharffetter-Kachanek, K. Severe toxic contact dermatitis caused by garlic.Fani, M.
M., Kohanteb, J., and Dayaghi, M. Inhibitory activity of garlic (Allium sativum) extract on multidrug-resistant Streptococcus mutans.Baluchnejadmojarad, T., Roghani, M., Homayounfar, H., and Hosseini, M. Beneficial effect of aqueous garlic extract on the vascular reactivity of streptozotocin-diabetic rats.Banerjee, S. K., Dinda, A. K., Manchanda, S. C., and Maulik, S.
K. Chronic garlic administration protects rat heart against oxidative stress induced by ischemic reperfusion injury.Effects of garlic oil on platelet aggregation, serum lipids and blood pressure in humans.A., and Orekhov, A.
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P., Agrawal, S., Indrayan, A., and Seth, P. Effect of garlic on normal blood cholesterol level.Bhuvaneswari, V., Abraham, S. K., and Nagini, S.
Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis.Bimmermann A, Weingart K, and Schwartzkopff W. Allium sativum: Studie zur Wirksamkeit bei Hyperlipoproteinamie.Bleumink, E., Doeglas, H.
M., Klokke, A. H., and Nater, J. P.
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K., Sanadhya, Y. K., and Bhu, N.
Effect of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery disease.Bordia, A., Bansal, H. C., Arora, S.
K., and Singh, S. V. Effect of the essential oils of garlic and onion on alimentary hyperlipemia.Bordia, A., Verma, S.
K., and Srivastava, K. C.
Effect of garlic on platelet aggregation in humans: a study in healthy subjects and patients with coronary artery disease.Bordia, T., Mohammed, N., Thomson, M., and Ali, M. An evaluation of garlic and onion as antithrombotic agents.B., and Eling, T.
E. Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells.Bradley R, Endres J, Hockenberry D, and et al.
Investigation of garlic-induced apoptosis in breast cancer cell lines [poster presentation].International Scientific Conference on Complementary, Alternative and Integrative Medicine Research, Boston, MA, 2002.Brosche, T., Platt, D., and Dorner, H. The effect of a garlic preparation on the composition of plasma lipoproteins and erythrocyte membranes in geriatric subjects.Budoff, M.
J., Takasu, J., Flores, F. R., Niihara, Y., Lu, B., Lau, B. H., Rosen, R.
T., and Amagase, H. Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study.Buiatti, E., Palli, D., Decarli, A., Amadori, D., Avellini, C., Bianchi, S., Biserni, R., Cipriani, F., Cocco, P., Giacosa, A., and .Byrne, D. J., Neil, H.
A., Vallance, D. T., and Winder, A. F. A pilot study of garlic consumption shows no significant effect on markers of oxidation or sub-fraction composition of low-density lipoprotein including lipoprotein(a) after allowance for non-compliance and the placebo effect.Canduela, V., Mongil, I., Carrascosa, M., Docio, S., and Cagigas, P. Garlic: always good for the health?Caporaso, N., Smith, S. M., and Eng, R.
H. Antifungal activity in human urine and serum after ingestion of garlic (Allium sativum).Challier, B., Perarnau, J. M., and Viel, J.
F. Garlic, onion and cereal fibre as protective factors for breast cancer: a French case-control study.Chauhan, N. B.
and Sandoval, J. Amelioration of early cognitive deficits by aged garlic extract in Alzheimer's transgenic mice.Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576.Chu, Q., Lee, D. T., Tsao, S.
W., Wang, X., and Wong, Y. C. S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions.Cohain, J. S. Long-term symptomatic group B streptococcal vulvovaginitis: eight cases resolved with freshly cut garlic.Das, I., Khan, N. S., and Sooranna, S.
R. Potent activation of nitric oxide synthase by garlic: a basis for its therapeutic applications.Das, I., Patel, S., and Sooranna, S.
R. Effects of aspirin and garlic on cyclooxygenase-induced chemiluminescence in human term placenta.In vitro synergism of concentrated allium sativum extract and amphotericin B against cryptococcus neoformans.Davis, L.
E., Shen, J. K., and Cai, Y. Antifungal activity in human cerebrospinal fluid and plasma after intravenous administration of Allium sativum.Davis, S. R., Perrie, R., and Apitz-Castro, R.
The in vitro susceptibility of Scedosporium prolificans to ajoene, allitridium and a raw extract of garlic (Allium sativum).de Rooij, B. M., Boogaard, P. J., Rijksen, D. A., Commandeur, J.
N., and Vermeulen, N. P. Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers.Delaha, E.
C. and Garagusi, V.
F. Inhibition of mycobacteria by garlic extract (Allium sativum).Demirkaya, E., Avci, A., Kesik, V., Karslioglu, Y., Oztas, E., Kismet, E., Gokcay, E., Durak, I., and Koseoglu, V. Cardioprotective roles of aged garlic extract, grape seed proanthocyanidin, and hazelnut on doxorubicin-induced cardiotoxicity.Deshpande, R. G., Khan, M.
B., Bhat, D. A., and Navalkar, R.
G. Inhibition of Mycobacterium avium complex isolates from AIDS patients by garlic (Allium sativum).Dhawan, V. and Jain, S. Effect of garlic supplementation on oxidized low density lipoproteins and lipid peroxidation in patients of essential hypertension.Dillon, S. A., Lowe, G. M., Billington, D., and Rahman, K.
Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women.Dirsch VM, Kiemer AK, Wagner H, and et al. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase.Dirsch, V.
M., Gerbes, A. L., and Vollmar, A.
M. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB.Dixit, V. P. and Joshi, S.
Effects of chronic administration of garlic (Allium sativum Linn) on testicular function.Abbruzzese, M. R., Delaha, E. C., and Garagusi, V.
F. Absence of antimycobacterial synergism between garlic extract and antituberculosis drugs.[Two cases of eosinophilic gastroenteritis whose causative allergens are usefully diagnosed by patch test].Adetumbi, M., Javor, G. T., and Lau, B.
H. Allium sativum (garlic) inhibits lipid synthesis by Candida albicans.Ahmad, M. S., Pischetsrieder, M., and Ahmed, N.
Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts.Ahmadi, N., Tsimikas, S., Hajsadeghi, F., Saeed, A., Nabavi, V., Bevinal, M. A., Kadakia, J., Flores, F., Ebrahimi, R., and Budoff, M. J.Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium.Ali, M. and Thomson, M. Consumption of a garlic clove a day could be beneficial in preventing thrombosis.Ali, M. Mechanism by which garlic (Allium sativum) inhibits cyclooxygenase activity.Effect of raw versus boiled garlic extract on the synthesis of prostanoids.Ambati, S., Yang, J.
Y., Rayalam, S., Park, H. J., Della-Fera, M.
A., and Baile, C. A.
Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis.Andrianova, I. V., Fomchenkov, I.
V., and Orekhov, A. N. [Hypotensive effect of long-acting garlic tablets allicor (a double-blind placebo-controlled trial)].A., Karabasova, IaA, Liutova, L.
I., Povorinskaia, T. E., and Orekhov, A. N. [Use of allikor for the normalization of fibrinolysis and hemostasis in patients with chronic cerebrovascular diseases].[Effect of long-acting garlic tablets "allicor" on the incidence of acute respiratory viral infections in children].Anim-Nyame, N., Sooranna, S. R., Johnson, M. R., Gamble, J., and Steer, P.
J. Garlic supplementation increases peripheral blood flow: a role for interleukin-6?Anthony, J. P., Fyfe, L., and Smith, H.
Plant active components - a resource for antiparasitic agents?Apitz-Castro, R., Escalante, J., Vargas, R., and Jain, M. K. Ajoene, the antiplatelet principle of garlic, synergistically potentiates the antiaggregatory action of prostacyclin, forskolin, indomethacin and dypiridamole on human platelets.Ashraf, M. Z., Hussain, M.
E., and Fahim, M. Endothelium mediated vasorelaxant response of garlic in isolated rat aorta: role of nitric oxide.Ashraf, R., Aamir, K., Shaikh, A. R., and Ahmed, T. Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus.Augusti, K.
T. and Sheela, C. G.
Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats.Effects of garlic consumption on plasma and erythrocyte antioxidant parameters in elderly subjects.Ayala-Zavala, J. F., Gonzalez-Aguilar, G. A., and Toro-Sanchez, L.
Enhancing safety and aroma appealing of fresh-cut fruits and vegetables using the antimicrobial and aromatic power of essential oils.Bagga, S., Thomas, B. S., and Bhat, M.
Garlic burn as self-inflicted mucosal injury--a case report and review of the literature.B., Shabestari, S. B., Tanik, A., and Pahlevan, R.
Comparison of therapeutic effect of aqueous extract of garlic and nystatin mouthwash in denture stomatitis.Bakri, I. M.
and Douglas, C. W. Inhibitory effect of garlic extract on oral bacteria.Balasenthil, S., Ramachandran, C. R., and Nagini, S.
Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic.Balasenthil, S., Rao, K. S., and Nagini, S. Altered cytokeratin expression during chemoprevention of experimental hamster buccal pouch carcinogenesis by garlic.Balasenthil, S., Rao, K.
S., and Nagini, S. Retinoic acid receptor-beta mRNA expression during chemoprevention of hamster cheek pouch carcinogenesis by garlic.Baluchnejadmojarad, T.
and Roghani, M. Endothelium-dependent and -independent effect of aqueous extract of garlic on vascular reactivity on diabetic rats.Anibarro B, Fontela JL, De La Hoz F. Occupational asthma induced by garlic dust.Asgharpour M, Khavandegar A, Balaei P, et al.
Efficacy of Oral Administration of Allium sativum Powder "Garlic Extract" on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients.Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension.Effects of garlic supplementation on oxidative stress and antioxidative capacity biomarkers: A systematic review and meta-analysis of randomized controlled trials.Aydin A, Ersoz G, Tekesin O, et al. Garlic oil and Helicobacter pylori infection.Bahadoran P, Rokni FK, Fahami F. Investigating the therapeutic effect of vaginal cream containing garlic and thyme compared to clotrimazole cream for the treatment of mycotic vaginitis.Berthold HK, Sudhop T, von Bergmann K.
Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism.Garlic (Allium sativum L.): adverse effects and drug interactions in humans.Protective effect of chronic garlic intake on elastic properties of aorta in the elderly.Calvet X, Carod C, Gene E. Re: Peppers at treatment for Helicobacter pylori infection.Effect of cooking on garlic (Allium sativum l.) Antiplatelet activity and thiosulfinates content.Effects of garlic on lipid metabolism in rats fed cholesterol or lard.Chiavarini M, Minelli L, Fabiani R. Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis.Choudhary PR, Jani RD, Sharma MS. Effect of raw crushed garlic (Allium sativum L.) on components of metabolic syndrome.The effect of fried versus raw garlic on fibrinolytic activity in man.Dehghani F, Merat A, Panjehshahin MR, Handjani F. Healing effect of garlic extract on warts and corns.The effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis.Desai G, Schelske-Santos M, Nazario CM, et al. Onion and garlic intake and breast cancer, a case-control study in Puerto Rico.Dev T, Bharti P, Patel U, Bhari N.
Chronic paronychia and nail dystrophy: an atypical presentation of allergic contact dermatitis to garlic.Dhamija P, Malhotra S, Pandhi P. Effect of oral administration of crude aqueous extract of garlic on pharmacokinetic parameters of isoniazid and rifampicin in rabbits.Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase.A prospective cohort study on Allium vegetable consumption, garlic supplement use, and the risk of lung carcinoma in The Netherlands.Allium vegetable consumption, garlic supplement intake, and female breast carcinoma incidence.A prospective cohort study on the relationship between onion and leek consumption, garlic supplement use and the risk of colorectal carcinoma in The Netherlands.An unusual case of HIV virologic failure during treatment with boosted atazanavir.The effect of the aged garlic extract, 'Kyolic', on the development of experimental atherosclerosis.Ernst E.
Is garlic an effective treatment for Helicobacter pylori infection?Fleischauer AT, Arab L. Garlic and cancer: a critical review of the epidemiologic literature.Effect of ingestion of raw garlic on serum cholesterol level, clotting time and fibrinolytic activity in normal subjects.Gallicano K, Foster B, Choudhri S.
Effect of short-term administration of garlic supplements on single-dose ritonavir pharmacokinetics in healthy volunteers.Gandomkar H, Mahmoodzadeh H, Tavakoli H, Fazeli M, Rezaei J. Garlic-induced esophageal perforation: A case series.The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults.Gardner CD, Lawson LD, Block E, et al.
Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial.Gebhardt R and Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures.Gebhardt R, Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures.Ghorai M, Mandal SC, Pal M, et al. A comparative study on hypocholesterolaemic effect of allicin, whole germinated seeds of bengal gram and guggulipid of gum gugglu.Graham DY, Anderson SY, Lang T. Garlic or jalapeno peppers for treatment of Helicobacter pylori infection.Relationship between consumption of raw garlic and handgrip strength in a large-scale adult population.Gurley BJ, Gardner SF, Hubbard MA, et al. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans.AAPS Ann Mtg & Expo Indianapolis, IN: 2000; Oct 29 - Nov 2:presentation #3460.Calabash chalk may pose health risk for pregnant and breastfeeding women.Horie T, Awazu S, Itakura Y, Fuwa T.
Alleviation by garlic of antitumor drug-induced damage to the intestine.Protective effect of aged garlic extract on the small intestinal damage of rats induced by methotrexate administration.Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials.Hsing AW, Chokkalingam AP, Gao YT, et al. Allium vegetables and risk of prostate cancer: a population-based study.Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes: A prospective randomized controlled double-blind study.Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury.Imai J, Ide N, Nagae S, et al.
Antioxidant and radical scavenging effects of aged garlic extract and its constituents.Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium.Isaacsohn JL, Moser M, Stein EA, et al. Garlic powder and plasma lipids and lipoproteins, a multicenter, randomized, placebo-controlled trial.Effect of Garlic (Allium sativum) Supplementation on Premenstrual Disorders: A Randomized, Double-Blind, Placebo-Controlled Trial.Jalloh MA, Gregory PJ, Hein D, et al.
Dietary supplement interactions with antiretrovirals: a systematic review.Effect of a combined supplementation of fish oil (MEGA-3) with garlic pearls on the serum lipid profile, blood pressure and body mass index of hypercholesterolemic subjects.Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices.Kenzelmann R, Kade F.
Limitation of the deterioration of lipid parameters by a standardized garlic-ginkgo combination product.Key TJ, Silcocks PB, Davey GK, et al. A case-control study of diet and prostate cancer.Effects of garlic extract on lipid profile in patients with coronary artery disease: A systematic review and meta-analysis of randomised clinical trials.Effects of garlic coated tablets in peripheral arterial occlusive disease.Kim H, Keum N, Giovannucci EL, Fuchs CS, Bao Y. Garlic intake and gastric cancer risk: results from two large prospective US cohort studies.Effect of garlic intake on inflammatory mediators: a systematic review and meta-analysis of randomised controlled trials.The potential application of Allium sativum (garlic) for the treatment of bladder cancer.Lau BS, Lam F, Wang-Cheng R.
Effect of an odor-modified garlic preparation on blood lipids.Le Marchand L, Hankin JH, Wilkens LR, et al. Dietary fiber and colorectal cancer risk.Ledezma E, DeSousa L, Jorquera A, et al.
Efficacy of ajoene, an organosulphur derived from garlic, in the short-term therapy of tinea pedis.Ledezma E, Marcano K, Jorquera A. Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine.Contact dermatitis due to topical treatment with garlic in Hong Kong.Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in healthy subjects.Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. .
Can You Eat Raw Garlic? Benefits and Downsides
Cooking garlic alters its taste and texture, making it softer, milder, and creamier and giving it a more subtle flavor and aroma.Interestingly, some research suggests that allicin could help enhance the function of your immune system and may offer some protection against conditions like heart disease and cancer ( 1 ).Several studies show that garlic may help decrease inflammation and boost immune function, which may be due to its content of antioxidants and sulfur-containing compounds like allicin ( 4 , 5 ).Several studies show that garlic may help decrease inflammation and boost immune function, which may be due to its content of antioxidants and sulfur-containing compounds like allicin ( , ).Some research suggests that garlic may help lower blood pressure and decrease cholesterol levels to support heart health ( 6 ).Some research suggests that garlic may help lower blood pressure and decrease cholesterol levels to support heart health ( ).Garlic has been shown to improve immunity, stabilize blood sugar levels, and support heart and brain health.In fact, certain compounds found in raw garlic may irritate the digestive tract, which could cause a burning sensation in the chest or stomach ( 12 ).Switching to cooked garlic instead of eating it raw may also help ease digestive side effects like heartburn or acid reflux ( 12 ). .
Garlic: Proven health benefits and uses
According to experts at Kew Gardens, England’s royal botanical center of excellence, the people of ancient India valued the therapeutic properties of garlic and also thought it to be an aphrodisiac.The original Olympic athletes in Ancient Greece were given garlic – possibly the earliest example of “performance enhancing” agents used in sports.A study published in the journal Food and Chemical Toxicology warned that short-term heating reduces the anti-inflammatory effects of fresh raw garlic extracts.Co-author, Ray Swapan, Ph.D., said “This research highlights the great promise of plant-originated compounds as natural medicine for controlling the malignant growth of human brain tumor cells.Women whose diets were rich in allium vegetables had lower levels of osteoarthritis , a team at King’s College London and the University of East Anglia, both in England, reported in the journal BMC Musculoskeletal Disorders.The study authors said their findings not only highlighted the possible impact of diet on osteoarthritis outcomes but also demonstrated the potential for using compounds that exist in garlic to develop treatments for the condition.The long-term study, involving more than 1,000 healthy female twins, found that those whose dietary habits included plenty of fruit and vegetables, “particularly alliums such as garlic,” had fewer signs of early osteoarthritis in the hip joint.Diallyl sulfide, a compound in garlic, was 100 times more effective than two popular antibiotics in fighting the Campylobacter bacterium, according to a study published in the Journal of Antimicrobial Chemotherapy.Senior author, Dr. Xiaonan Lu, from Washington State University, said, “This work is very exciting to me because it shows that this compound has the potential to reduce disease-causing bacteria in the environment and in our food supply.”.Because of this, the scientists decided to focus on diallyl trisulfide, a garlic oil component, as a safer way to deliver the benefits of hydrogen sulfide to the heart.In another study, published in the Journal of Agricultural and Food Chemistry, scientists found that garlic oil may help protect diabetes patients from cardiomyopathy.The study authors wrote, “In conclusion, garlic oil possesses significant potential for protecting hearts from diabetes-induced cardiomyopathy.”.Doctors at the Department of Urology, China-Japan Friendship Hospital, Beijing, China, carried out a study evaluating the relationship between Allium vegetable consumption and prostate cancer risk.Scientists at the Institute of Toxicology, School of Public Health, Shandong University, China, wanted to determine whether diallyl disulfide (DADS), a garlic-derived organosulfur compound, might have protective effects against ethanol-induced oxidative stress.Scientists at the Division of Epidemiology, Norwegian Institute of Public Health, studied what impact foods might have on antimicrobial infections and preterm delivery risk.Ronny Myhre and colleagues concentrated on the effects of Alliums and dried fruits, because a literature search had identified these two foods as showing the greatest promise for reducing preterm delivery risk.The team investigated the intake of dried fruit and Alliums among 18,888 women in the Norwegian Mother and Child Cohort, of whom 5 percent (950) underwent spontaneous PTD (preterm delivery).The study authors concluded, “Intake of food with antimicrobial and prebiotic compounds may be of importance to reduce the risk of spontaneous PTD. .
7 Impressive Benefits of Garlic
Indeed, “in many studies, the concentrated equivalent may be around two cloves,” says Wendy Bazilian, RDN, a doctor of public health and nutritionist in San Diego and author of the Eat Clean, Stay Lean book series.But don’t discount the power of adding garlic to your favorite foods, which can contain a huge variety of nutrients and chemicals that may interact synergistically together in beneficial ways, says Raj.Don’t be afraid to load up the garlic in hummus, pesto, pasta, sauces, soups, stir-fries, and roasted vegetables, says Dr. Bazilian.“Garlic stimulates the synthesis of nitric oxide, which dilates blood vessels, and inhibits ACE (angiotensin-converting enzyme) activity,” says Raj.Given our collective zest for learning about taking care of our immune system during the COVID-19 pandemic, here’s one reason to add garlic to your dinner tonight.While there’s not enough evidence to suggest that that garlic will prevent or treat the common cold, for instance, it can play a role in your body’s defense mechanisms in a few ways.Scientists also believe that garlic has antiviral properties that may work in two ways, she says: by blocking the entry of viruses into cells, and by strengthening the immune response so that it can effectively fight off potential invaders.The National Heart, Blood, and Lung Institute recommends following a heart-healthy eating plan, getting plenty of exercise, managing your weight, and avoiding or quitting smoking.Adding flavor through garlic can also potentially help you reduce the need for excess salt on your foods — and for just 4 calories per clove, according to the U.S.
Department of Agriculture.And finally, don’t discount the role that taste plays in your overall diet: “When we love the food we eat and learn to listen to our cues for satiety, it can be more satisfying, too,” Bazilian says. .
Health Effects of Garlic
A more recent meta-analysis10 of placebo-controlled trials using standardized dried garlic powder showed significant reductions in total cholesterol levels (19.2 mg per dL [0.50 mmol per L]), low-density lipoprotein cholesterol levels (6.7 mg per dL [0.20 mmol per L]) and triglyceride levels (21.1 mg per dL [0.24 mmol per L]) at eight to 12 weeks; these reductions were not sustained at six months of treatment. .
The Top 8 Health Benefits of Garlic
For thousands of years, before this spice was used to flavor your favorite dishes, it was employed as a medical treatment in ancient cultures.Garlic consumption has been shown to have numerous fantastic health benefits for the body.Though it was not widely known, experts now understand that sulfur compounds in garlic are the primary cause of its beneficial effects on health.By slicing, chopping, or crushing garlic bulbs, the thio-Sulfinite chemicals in them are converted into allicin.Your body’s immunity is what keeps it from getting sick in the first place, and it also aids in the fight against illness when the situation calls for it.Garlic offers an immune system boost to help prevent colds and the flu virus.In some households around the world, families hang garlic cloves on a string around their childrens’ necks to help them with congestion.Because they are among the significant causes of death, addressing one of their primary causes, high blood pressure, is extremely important.Garlic is a fantastic spice to include in your diet for those suffering from high blood pressure or hypertension.Keep in mind that you must make sure that the amount of these supplements you take is the same as four cloves of garlic each day.According to research, consuming fresh garlic can help lessen the risk of colon cancer.Allicin is a bioactive antibiotic that can help fight infections and bacteria in sliced, squashed, or diced cloves.Garlic has high antioxidants, which help prevent any oxidative damage from occurring in your body.Garlic was used in the olden days to alleviate weariness and boost laborers’ working hours and endurance.Ultimately, eating garlic plays an excellent role in minimizing, even if subtly, how soon you get weary when physically exerting yourself.We are exposed to a wide range of chemicals and compounds daily while living in the world today.Garlic is a powerful detox food that promotes glutathione production by various liver enzymes.It also provides other important detoxifying components, including multiple bioactive selenium and sulfur compounds.Now that we have discussed the health benefits of garlic, whether raw or taken as a supplement, you can take the first step to a healthier, better you.Then contact us whether you prefer conveniently minced garlic, easy-to-use peeled cloves or whole bulbs. .
Is It Okay to Eat a Raw Garlic Clove? 10 Health Benefits
Also, having a large amount of garlic at once may give you a burning sensation inside the mouth, heartburn, gases, and loose bowel movements.Garlic is found as a white bulb (the shape is similar to an onion).Most of the benefits of raw garlic come from an enzyme called allicinAllicin has anti-inflammatory, antioxidative, antibacterial, and anticancer properties. .
