It’s claimed to cause weight loss by reducing appetite and cravings.What Is Spinach Extract?Spinach extract is a weight loss supplement made from spinach leaves.In fact, they’re found in the leaves of all green plants — and similar supplements could be made from those plants as well.SUMMARY Spinach extract — also known as Appethyl — is a weight loss supplement.SUMMARY Spinach extract promotes weight loss by delaying fat digestion, temporarily reducing appetite, and causing you to eat less.SUMMARY Studies show that taking spinach extract supplements for a few months may cause weight loss.Another study in women suggests that 5 grams of spinach extract reduces cravings for snack foods, including those that are salty, sweet, and fatty.Safety and Side Effects Spinach extract appears to be without serious side effects.In healthy people, it may temporarily reduce insulin levels and increase blood sugar.However, you may need to take it for a few months before you see any effects on your weight ( 6 ). .

## Could a spinach extract help with weight loss?

"The membranes around those chloroplasts, which are a component of most green leaves, can bind with the two hormones or enzymes that come out from the pancreas when you eat fat,” said Dr. Frank Greenway, Chief Medical Officer at the Pennington Biomedical Research Center in Baton Rouge.Researchers examined the effect of taking the concentrated extract of spinach thylakoids on appetite, food intake and satiety compared to the placebo.Greenway said when people eat foods containing fats, the thylakoids in spinach restrain certain hormones activated by the fatty foods.Researchers believe the concentrated spinach extract helps with weight loss.“It’s been shown that it can cause some weight loss...like over a 90-day period there was about 5 kilograms of weight loss from the spinach.A different study concluded that overweight women consuming five grams of the spinach extract for three months demonstrated a 43 percent greater loss of body weight compared to those who took a placebo. .

## Spinach supplement may increase muscle strength

New research has examined the potential of spinach extract as an enhancer of athletic performance.The active compound in spinach extract significantly improves muscle strength, leading the study authors to recommend banning the supplement in sports. .

## Effects of spinach extract on satiety: Feel full, curb cravings

A new study found in the Journal of the American College of Nutrition examines how consuming the concentrated extract of thylakoids found in spinach can reduce hunger and cravings.The study examines the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. .

## Spinach extract effect potent enough to feature on WADA banned list

Its potency is such that the researchers recommend its inclusion on WADA’s prohibited substances and methods in sports in class S1.2 “other anabolic agents”.​.The PL group took two placebo capsules each day over the same period.The CO group took only two capsules of the dietary supplement without training.After the ten-week study period, the athletes who took ecdysterone showed a significantly higher increase in maximum muscle strength.The PL group improved their squat from 107.5kg to 124.17kg.The team also identified 6mg of ecdysterone per capsule for this product.“Ecdysteroids as non​‑conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans.”​. .

## The effects of thylakoid-rich spinach extract and aqueous extract of

Spinach leaves were frozen directly after harvest and kept so until the extraction procedure.Determining the content of chlorophyll content is one method to measure the amount of thylakoid membranes [17].Initially, 60 non-pregnant female Sprague-Dawley rats (aged 10–12 weeks and weighing 180-220 g) were acquired from the Laboratory Animals Research Center (Shiraz University of Medical Sciences, Iran).Before the induction of PCOS, vaginal smears were collected from all animals for 2 weeks to evaluate the regularity of their reproductive cycle.In the present study, animals were divided randomly into five equal groups of 12 rats each:.Metformin group: PCOS-induced rats that received metformin (Shafa Pharmaceutical Co., Tehran, IRAN) dissolved in normal saline at a level of 150 mg/kg body weight/day.Thus, the treatment dose of thylakoid can reflect the chlorophyll content of the extract [17].Collection of blood samples.All the serum samples were stored in clean sterile micro-centrifuge tubes at − 80 ∘C until further analysis.E0707Ra) was used to determine the serum insulin concentrations.From each ovary, 8–12 sections were sampled randomly.Counting probe was randomly placed on the images; then, the total number of points hitting the sections was counted (Fig.The volume density of the targeted structure (here cortex, medulla, corpus luteum, and ovarian cysts) was estimated on 5 μm-thick sections through the point-counting method and using Delesse formula [19] (Fig.In which ‘$${\sum}_{i=1}^np(structure)$$’ is the number of the test points falling on the targeted structure (here cortex, medulla, corpus luteum, and ovarian cysts) and ‘$${\sum}_{i=1}^np$$ (reference)’ is the total points hitting the ovary sections.The number of follicles was determined on 20 μm-thick sections using an optical disector method (Fig.In this formula, ‘$${\sum}_{i=1}^nQ$$’ is the number of the follicles counted in all of the dissectors, ‘h’ the height of the optical disector, ‘a/f’ the area of the counting frame, ‘$${\sum}_{i=1}^nP$$’ the total number of the counted frames, ‘BA’ (block advance) the setting of the microtome to cut the paraffin block, and ‘t’ the mean of the final section thickness [28].Repeated measures ANOVA was used to compare the mean body weight between groups at different measurement times.For all of the study markers, at first a comparison between the sham group and PCOS control group were done to be sure that markers in the PCOS control group is different significantly with the sham group.Then, we compared the study parameters between the treated groups and the PCOS control group. .

## Suppressive effect of spinach extract on the formation of melanin in

Akiu S, Suzuki Y, Fujinuma Y, Asahara T, and Fukuda M (1988) Inhibitory effect of arbutin on melanogenesis: Biochemical study in cultured B16 melanoma cells and effect on the UV-induced pigmentation in human skin.Proc.Jpn.Soc.Pigment Cell Res. .

## Consumption of thylakoid-rich spinach extract reduces hunger

The purpose of this study was to investigate how treatment with a single dose of thylakoids before breakfast affects homeostatic as well as hedonic hunger, measured as wanting and liking for palatable food (VAS). .

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